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Paracetamol is a common agent taken in deliberate self‐poisoning and in accidental overdose in adults and children. Paracetamol poisoning is the commonest cause of severe acute liver injury. 

Since the publication of the previous guidelines in 2015, several studies have changed practice. A working group of experts in the area, with representation from all Poisons Information Centres of Australia and New Zealand, were brought together to produce an updated evidence‐based guidance.

This MJA guideline summary shares more.

Details

• Explain key components of the revised guideline.
• List main recommendations.
• Recognise changes in management as a result of the revised guideline.

Authors: Angela L Chiew, David Reith, Adam Pomerleau, Anselm Wong, Katherine Z Isoardi, Jessamine Soderstrom, Nicholas A Buckley

Article Type: Guideline summary